Pretraining strategies for effective promoter-driven gene expression prediction

Advances in gene delivery technologies are enabling rapid progress in molecular medicine, but require precise expression of genetic cargo in desired cell types, which is predominantly achieved via a regulatory DNA sequence called a promoter; however, only a handful of cell type-specific promoters ar...

Descripción completa

Detalles Bibliográficos
Autores principales: Reddy, Aniketh Janardhan, Herschl, Michael H., Kolli, Sathvik, Lu, Amy X., Geng, Xinyang, Kumar, Aviral, Hsu, Patrick D., Levine, Sergey, Ioannidis, Nilah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002662/
https://www.ncbi.nlm.nih.gov/pubmed/36909524
http://dx.doi.org/10.1101/2023.02.24.529941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002662/
https://www.ncbi.nlm.nih.gov/pubmed/36909524
http://dx.doi.org/10.1101/2023.02.24.529941

Ejemplares similares