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Pretraining strategies for effective promoter-driven gene expression prediction
Advances in gene delivery technologies are enabling rapid progress in molecular medicine, but require precise expression of genetic cargo in desired cell types, which is predominantly achieved via a regulatory DNA sequence called a promoter; however, only a handful of cell type-specific promoters ar...
Autores principales: | Reddy, Aniketh Janardhan, Herschl, Michael H., Kolli, Sathvik, Lu, Amy X., Geng, Xinyang, Kumar, Aviral, Hsu, Patrick D., Levine, Sergey, Ioannidis, Nilah M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002662/ https://www.ncbi.nlm.nih.gov/pubmed/36909524 http://dx.doi.org/10.1101/2023.02.24.529941 |
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