Structural homology screens reveal poxvirus-encoded proteins impacting inflammasome-mediated defenses

Viruses acquire host genes via horizontal gene transfer and can express them to manipulate host biology during infections. Some viral and host homologs retain sequence identity, but evolutionary divergence can obscure host origins. We used structural modeling to compare vaccinia virus proteins with...

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Detalles Bibliográficos
Autores principales: Boys, Ian N., Johnson, Alex G., Quinlan, Meghan, Kranzusch, Philip J., Elde, Nels C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002665/
https://www.ncbi.nlm.nih.gov/pubmed/36909515
http://dx.doi.org/10.1101/2023.02.26.529821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002665/
https://www.ncbi.nlm.nih.gov/pubmed/36909515
http://dx.doi.org/10.1101/2023.02.26.529821

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