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Structural homology screens reveal poxvirus-encoded proteins impacting inflammasome-mediated defenses
Viruses acquire host genes via horizontal gene transfer and can express them to manipulate host biology during infections. Some viral and host homologs retain sequence identity, but evolutionary divergence can obscure host origins. We used structural modeling to compare vaccinia virus proteins with...
Autores principales: | Boys, Ian N., Johnson, Alex G., Quinlan, Meghan, Kranzusch, Philip J., Elde, Nels C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002665/ https://www.ncbi.nlm.nih.gov/pubmed/36909515 http://dx.doi.org/10.1101/2023.02.26.529821 |
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