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Detecting the effect of genetic diversity on brain composition in an Alzheimer’s disease mouse model

Alzheimer’s disease (AD) is characterized by neurodegeneration, pathology accumulation, and progressive cognitive decline. There is significant variation in age at onset and severity of symptoms highlighting the importance of genetic diversity in the study of AD. To address this, we analyzed cell an...

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Detalles Bibliográficos
Autores principales: Gurdon, Brianna, Yates, Sharon C., Csucs, Gergely, Groeneboom, Nicolaas E., Hadad, Niran, Telpoukhovskaia, Maria, Ouellette, Andrew, Ouellette, Tionna, O’Connell, Kristen, Singh, Surjeet, Murdy, Tom, Merchant, Erin, Bjerke, Ingvild, Kleven, Heidi, Schlegel, Ulrike, Leergaard, Trygve B., Puchades, Maja A., Bjaalie, Jan G., Kaczorowski, Catherine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002670/
https://www.ncbi.nlm.nih.gov/pubmed/36909528
http://dx.doi.org/10.1101/2023.02.27.530226