Ultrasensitive response explains the benefit of combination chemotherapy despite drug antagonism

Most aggressive lymphomas are treated with combination chemotherapy, commonly as multiple cycles of concurrent drug administration. Concurrent administration is in theory optimal when combination therapies have synergistic (more than additive) drug interactions. We investigated pharmacodynamic inter...

Descripción completa

Detalles Bibliográficos
Autores principales: Patterson, Sarah C., Pomeroy, Amy E., Palmer, Adam C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002679/
https://www.ncbi.nlm.nih.gov/pubmed/36909518
http://dx.doi.org/10.1101/2023.02.27.530263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002679/
https://www.ncbi.nlm.nih.gov/pubmed/36909518
http://dx.doi.org/10.1101/2023.02.27.530263

Ejemplares similares