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Discovery of decreased ferroptosis in male colorectal cancer patients with KRAS mutations

Aberrant tumor metabolism is a hallmark of cancer in which metabolic rewiring can support tumor growth under nutrient deficient conditions. KRAS mutations occur in 35–45% of all colorectal cancer (CRC) cases and are difficult to treat. The relationship between mutant KRAS and aberrant metabolism in...

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Detalles Bibliográficos
Autores principales: Yan, Hong, Talty, Ronan, Jain, Abhishek, Cai, Yuping, Zheng, Jie, Shen, Xinyi, Muca, Engjel, Paty, Philip B., Bosenberg, Marcus W., Khan, Sajid A., Johnson, Caroline H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002683/
https://www.ncbi.nlm.nih.gov/pubmed/36909561
http://dx.doi.org/10.1101/2023.02.28.530478