Induction of viral mimicry upon loss of DHX9 and ADAR1 in breast cancer cells

Detection of viral double-stranded RNA (dsRNA) is an important component of innate immunity. However, many endogenous RNAs containing double-stranded regions can be misrecognized and activate innate immunity. The interferon inducible ADAR1-p150 suppresses dsRNA sensing, an essential function for ADA...

Descripción completa

Detalles Bibliográficos
Autores principales: Cottrell, Kyle A., Ryu, Sua, Torres, Luisangely Soto, Schab, Angela M., Weber, Jason D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002699/
https://www.ncbi.nlm.nih.gov/pubmed/36909617
http://dx.doi.org/10.1101/2023.02.27.530307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002699/
https://www.ncbi.nlm.nih.gov/pubmed/36909617
http://dx.doi.org/10.1101/2023.02.27.530307

Ejemplares similares