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Active maintenance of CD8(+) T cell naïvety through regulation of global genome architecture
The differentiation of naïve CD8(+) cytotoxic T lymphocytes (CTLs) into effector and memory states results in large scale changes in transcriptional and phenotypic profiles. Little is known about how large-scale changes in genome organisation reflect or underpin these transcriptional programs. We ut...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002700/ https://www.ncbi.nlm.nih.gov/pubmed/36909629 http://dx.doi.org/10.1101/2023.02.26.530139 |