Active maintenance of CD8(+) T cell naïvety through regulation of global genome architecture

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The differentiation of naïve CD8(+) cytotoxic T lymphocytes (CTLs) into effector and memory states results in large scale changes in transcriptional and phenotypic profiles. Little is known about how large-scale changes in genome organisation reflect or underpin these transcriptional programs. We ut...

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Detalles Bibliográficos
Autores principales: Russ, Brendan E., Tsyganov, Kirril, Quon, Sara, Yu, Bingfei, Li, Jasmine, Lee, Jason K. C., Olshansky, Moshe, He, Zhaohren, Harrison, Paul F., Barugahare, Adele, See, Michael, Nussing, Simone, Morey, Alison E., Udupa, Vibha A., Bennett, Taylah .J, Kallies, Axel, Murre, Cornelis, Collas, Phillipe, Powell, David, Goldrath, Ananda W., Turner, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002700/
https://www.ncbi.nlm.nih.gov/pubmed/36909629
http://dx.doi.org/10.1101/2023.02.26.530139
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