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Benchmarking differential abundance methods for finding condition-specific prototypical cells in multi-sample single-cell datasets
Modern single-cell data analysis relies on statistical testing (e.g. differential expression testing) to identify genes or proteins that are up-or down-regulated in relation to cell-types or clinical outcomes. However, existing algorithms for such statistical testing are often limited by technical n...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002703/ https://www.ncbi.nlm.nih.gov/pubmed/36909641 http://dx.doi.org/10.1101/2023.02.24.529894 |