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Benchmarking differential abundance methods for finding condition-specific prototypical cells in multi-sample single-cell datasets

Modern single-cell data analysis relies on statistical testing (e.g. differential expression testing) to identify genes or proteins that are up-or down-regulated in relation to cell-types or clinical outcomes. However, existing algorithms for such statistical testing are often limited by technical n...

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Detalles Bibliográficos
Autores principales: Yi, Haidong, Plotkin, Alec, Stanley, Natalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002703/
https://www.ncbi.nlm.nih.gov/pubmed/36909641
http://dx.doi.org/10.1101/2023.02.24.529894