Mass spectrometric profiling of HLA-B44 peptidomes provides evidence for tapasin-mediated tryptophan editing

Activation of CD8(+) T cells against pathogens and cancers involves the recognition of antigenic peptides bound to human leukocyte antigen (HLA) class-I proteins. Peptide binding to HLA class I proteins is coordinated by a multi-protein complex called the peptide loading complex (PLC). Tapasin, a ke...

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Detalles Bibliográficos
Autores principales: Kaur, Amanpreet, Surnilla, Avrokin, Zaitouna, Anita J., Basrur, Venkatesha, Mumphrey, Michael B., Grigorova, Irina, Cieslik, Marcin, Carrington, Mary, Nesvizhskii, Alexey I., Raghavan, Malini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002704/
https://www.ncbi.nlm.nih.gov/pubmed/36909546
http://dx.doi.org/10.1101/2023.02.26.530125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002704/
https://www.ncbi.nlm.nih.gov/pubmed/36909546
http://dx.doi.org/10.1101/2023.02.26.530125

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