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Mass spectrometric profiling of HLA-B44 peptidomes provides evidence for tapasin-mediated tryptophan editing
Activation of CD8(+) T cells against pathogens and cancers involves the recognition of antigenic peptides bound to human leukocyte antigen (HLA) class-I proteins. Peptide binding to HLA class I proteins is coordinated by a multi-protein complex called the peptide loading complex (PLC). Tapasin, a ke...
Autores principales: | Kaur, Amanpreet, Surnilla, Avrokin, Zaitouna, Anita J., Basrur, Venkatesha, Mumphrey, Michael B., Grigorova, Irina, Cieslik, Marcin, Carrington, Mary, Nesvizhskii, Alexey I., Raghavan, Malini |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002704/ https://www.ncbi.nlm.nih.gov/pubmed/36909546 http://dx.doi.org/10.1101/2023.02.26.530125 |
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