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Interpreting population and family-based genome-wide association studies in the presence of confounding
A central aim of genome-wide association studies (GWASs) is to estimate direct genetic effects: the causal effects on an individual’s phenotype of the alleles that they carry. However, estimates of direct effects can be subject to genetic and environmental confounding, and can also absorb the ‘indir...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002712/ https://www.ncbi.nlm.nih.gov/pubmed/36909521 http://dx.doi.org/10.1101/2023.02.26.530052 |