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Whole genome sequencing of Borrelia burgdorferi isolates reveals linked clusters of plasmid-borne accessory genome elements associated with virulence

Lyme disease is the most common vector-borne disease in North America and Europe. The clinical manifestations of Lyme disease vary based on the genospecies of the infecting Borrelia burgdorferi spirochete, but the microbial genetic elements underlying these associations are not known. Here, we repor...

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Detalles Bibliográficos
Autores principales: Lemieux, Jacob E., Huang, Weihua, Hill, Nathan, Cerar, Tjasa, Freimark, Lisa, Hernandez, Sergio, Luban, Matteo, Maraspin, Vera, Bogovic, Petra, Ogrinc, Katarina, Ruzic-Sabljic, Eva, Lapierre, Pascal, Lasek-Nesselquist, Erica, Singh, Navjot, Iyer, Radha, Liveris, Dionysios, Reed, Kurt D., Leong, John M., Branda, John A., Steere, Allen C., Wormser, Gary P., Strle, Franc, Sabeti, Pardis C., Schwartz, Ira, Strle, Klemen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002713/
https://www.ncbi.nlm.nih.gov/pubmed/36909473
http://dx.doi.org/10.1101/2023.02.26.530159