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Whole genome sequencing of Borrelia burgdorferi isolates reveals linked clusters of plasmid-borne accessory genome elements associated with virulence
Lyme disease is the most common vector-borne disease in North America and Europe. The clinical manifestations of Lyme disease vary based on the genospecies of the infecting Borrelia burgdorferi spirochete, but the microbial genetic elements underlying these associations are not known. Here, we repor...
Autores principales: | Lemieux, Jacob E., Huang, Weihua, Hill, Nathan, Cerar, Tjasa, Freimark, Lisa, Hernandez, Sergio, Luban, Matteo, Maraspin, Vera, Bogovic, Petra, Ogrinc, Katarina, Ruzic-Sabljic, Eva, Lapierre, Pascal, Lasek-Nesselquist, Erica, Singh, Navjot, Iyer, Radha, Liveris, Dionysios, Reed, Kurt D., Leong, John M., Branda, John A., Steere, Allen C., Wormser, Gary P., Strle, Franc, Sabeti, Pardis C., Schwartz, Ira, Strle, Klemen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002713/ https://www.ncbi.nlm.nih.gov/pubmed/36909473 http://dx.doi.org/10.1101/2023.02.26.530159 |
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