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GIPC3 couples to MYO6 and PDZ domain proteins and shapes the hair cell apical region

GIPC3 has been implicated in auditory function. Initially localized to the cytoplasm of inner and outer hair cells of the cochlea, GIPC3 increasingly concentrated in cuticular plates and at cell junctions during postnatal development. Early postnatal Gipc3(KO/KO) mice had mostly normal mechanotransd...

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Detalles Bibliográficos
Autores principales: Chatterjee, Paroma, Morgan, Clive P., Krey, Jocelyn F., Benson, Connor, Goldsmith, Jennifer, Bateschell, Michael, Ricci, Anthony J., Barr-Gillespie, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002731/
https://www.ncbi.nlm.nih.gov/pubmed/36909580
http://dx.doi.org/10.1101/2023.02.28.530466