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Logic-based mechanistic machine learning on high-content images reveals how drugs differentially regulate cardiac fibroblasts
Fibroblasts are essential regulators of extracellular matrix deposition following cardiac injury. These cells exhibit highly plastic responses in phenotype during fibrosis in response to environmental stimuli. Here, we test whether and how candidate anti-fibrotic drugs differentially regulate measur...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002757/ https://www.ncbi.nlm.nih.gov/pubmed/36909540 http://dx.doi.org/10.1101/2023.03.01.530599 |