Simple In Vitro (18)O Labeling for Improved Mass Spectrometry-Based Drug Metabolites Identification: Deep Drug Metabolism Study

The identification of drug metabolites formed with different in vitro systems by HPLC-MS is a standard step in preclinical research. In vitro systems allow modeling of real metabolic pathways of a drug candidate. Despite the emergence of various software and databases, identification of compounds is...

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Detalles Bibliográficos
Autores principales: Tupertsev, Boris, Osipenko, Sergey, Kireev, Albert, Nikolaev, Eugene, Kostyukevich, Yury
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002766/
https://www.ncbi.nlm.nih.gov/pubmed/36902002
http://dx.doi.org/10.3390/ijms24054569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002766/
https://www.ncbi.nlm.nih.gov/pubmed/36902002
http://dx.doi.org/10.3390/ijms24054569

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