Transcriptional buffering and 3ʹUTR lengthening are shaped during human neurodevelopment by shifts in mRNA stability and microRNA load

The contribution of mRNA half-life is commonly overlooked when examining changes in mRNA abundance during development. mRNA levels of some genes are regulated by transcription rate only, but others may be regulated by mRNA half-life only shifts. Furthermore, transcriptional buffering is predicted wh...

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Detalles Bibliográficos
Autores principales: Mufteev, Marat, Rodrigues, Deivid C., Yuki, Kyoko E., Narula, Ashrut, Wei, Wei, Piekna, Alina, Liu, Jiajie, Pasceri, Peter, Rissland, Olivia S., Wilson, Michael D., Ellis, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002768/
https://www.ncbi.nlm.nih.gov/pubmed/36909614
http://dx.doi.org/10.1101/2023.03.01.530249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002768/
https://www.ncbi.nlm.nih.gov/pubmed/36909614
http://dx.doi.org/10.1101/2023.03.01.530249

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