Genome-scale requirements for dynein-based trafficking revealed by a high-content arrayed CRISPR screen

The cytoplasmic dynein-1 (dynein) motor plays a key role in cellular organisation by transporting a wide variety of cellular constituents towards the minus ends of microtubules. However, relatively little is known about how the biosynthesis, assembly and functional diversity of the motor is orchestr...

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Detalles Bibliográficos
Autores principales: Wong, Chun Hao, Wingett, Steven W., Qian, Chen, Taliaferro, J. Matthew, Ross-Thriepland, Douglas, Bullock, Simon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002790/
https://www.ncbi.nlm.nih.gov/pubmed/36909483
http://dx.doi.org/10.1101/2023.03.01.530592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002790/
https://www.ncbi.nlm.nih.gov/pubmed/36909483
http://dx.doi.org/10.1101/2023.03.01.530592

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