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Genome-scale requirements for dynein-based trafficking revealed by a high-content arrayed CRISPR screen
The cytoplasmic dynein-1 (dynein) motor plays a key role in cellular organisation by transporting a wide variety of cellular constituents towards the minus ends of microtubules. However, relatively little is known about how the biosynthesis, assembly and functional diversity of the motor is orchestr...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002790/ https://www.ncbi.nlm.nih.gov/pubmed/36909483 http://dx.doi.org/10.1101/2023.03.01.530592 |