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Hydroxymethylation alterations in progenitor-like cell types of pediatric central nervous system tumors are associated with cell type-specific transcriptional changes

Although intratumoral heterogeneity has been established in pediatric central nervous system tumors, epigenomic alterations at the cell type level have largely remained unresolved. To identify cell type-specific alterations to cytosine modifications in pediatric central nervous system tumors we util...

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Detalles Bibliográficos
Autores principales: Lee, Min Kyung, Azizgolshani, Nasim, Zhang, Ze, Perreard, Laurent, Kolling, Fred W., Nguyen, Lananh N., Zanazzi, George J., Salas, Lucas A., Christensen, Brock C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002842/
https://www.ncbi.nlm.nih.gov/pubmed/36909536
http://dx.doi.org/10.21203/rs.3.rs-2517758/v1