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Utility of Polygenic Risk Scoring to Predict Cognitive Impairment as Measured by Preclinical Alzheimer Cognitive Composite Score

BACKGROUND: The utility of Polygenic Risk Scores (PRS) is gaining increasing attention for generating an individual genetic risk profile to predict subsequent likelihood of future onset of Alzheimer’s disease (AD), especially those carry two copies of the APOE E3 allele, currently considered at neut...

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Detalles Bibliográficos
Autores principales: Gao, Q., Daunt, P., Gibson, A.M., Pither, R.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SERDI Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002888/
https://www.ncbi.nlm.nih.gov/pubmed/36923235
http://dx.doi.org/10.14283/jarlife.2022.1