Toxicity Study and Binding Analysis of Newly Synthesized Antifungal N-(4-aryl/cyclohexyl)-2-(pyridine-4-yl carbonyl) hydrazinecarbothioamide Derivative with Bovine Serum Albumin

The presence of the p-aryl/cyclohexyl ring in the N-(4-aryl/cyclohexyl)-2-(pyridine-4-yl carbonyl) hydrazine carbothioamide derivative (2C) is reported to enhance the antifungal properties when compared to those of itraconazole. Serum albumins present in plasma bind and transport ligands, including...

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Detalles Bibliográficos
Autores principales: Wani, Tanveer A., Bakheit, Ahmed H., Zargar, Seema, Altwaijry, Nojood, Bhat, Mashooq Ahmad, Alkahtani, Hamad M., Al-Rasheed, Lamees S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002925/
https://www.ncbi.nlm.nih.gov/pubmed/36902371
http://dx.doi.org/10.3390/ijms24054942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002925/
https://www.ncbi.nlm.nih.gov/pubmed/36902371
http://dx.doi.org/10.3390/ijms24054942

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