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In Silico Screening and Molecular Dynamics Simulation Studies in the Identification of Natural Compound Inhibitors Targeting the Human Norovirus RdRp Protein to Fight Gastroenteritis

Norovirus (HNoV) is a leading cause of gastroenteritis globally, and there are currently no treatment options or vaccines available to combat it. RNA-dependent RNA polymerase (RdRp), one of the viral proteins that direct viral replication, is a feasible target for therapeutic development. Despite th...

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Detalles Bibliográficos
Autores principales: Obaid, Rami J., Shafie, Alaa, Malik, M. Shaheer, Al-Rooqi, Munirah M., Moussa, Ziad, Abdulaziz, Osama, Aljuaid, Abdulelah, Allahyani, Mamdouh, Almehmadi, Mazen, Anjum, Farah, Ahmed, Saleh A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002960/
https://www.ncbi.nlm.nih.gov/pubmed/36902433
http://dx.doi.org/10.3390/ijms24055003