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Expression of pH-Sensitive GPCRs in Peritoneal Carcinomatosis of Colorectal Cancer—First Results

Solid tumors have an altered metabolism with a so-called inside-out pH gradient (decreased pH(e) < increased pH(i)). This also signals back to tumor cells via proton-sensitive ion channels or G protein-coupled receptors (pH-GPCRs) to alter migration and proliferation. Nothing, however, is known a...

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Detalles Bibliográficos
Autores principales: von Breitenbuch, Philipp, Kurz, Bernadett, Wallner, Susanne, Zeman, Florian, Brochhausen, Christoph, Schlitt, Hans-Jürgen, Schreml, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003041/
https://www.ncbi.nlm.nih.gov/pubmed/36902589
http://dx.doi.org/10.3390/jcm12051803