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Expression of pH-Sensitive GPCRs in Peritoneal Carcinomatosis of Colorectal Cancer—First Results
Solid tumors have an altered metabolism with a so-called inside-out pH gradient (decreased pH(e) < increased pH(i)). This also signals back to tumor cells via proton-sensitive ion channels or G protein-coupled receptors (pH-GPCRs) to alter migration and proliferation. Nothing, however, is known a...
Autores principales: | von Breitenbuch, Philipp, Kurz, Bernadett, Wallner, Susanne, Zeman, Florian, Brochhausen, Christoph, Schlitt, Hans-Jürgen, Schreml, Stephan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003041/ https://www.ncbi.nlm.nih.gov/pubmed/36902589 http://dx.doi.org/10.3390/jcm12051803 |
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