Resveratrol Modulates Chemosensitisation to 5-FU via β1-Integrin/HIF-1α Axis in CRC Tumor Microenvironment

Frequent development of resistance to chemotherapeutic agents such as 5-flourouracil (5-FU) complicates the treatment of advanced colorectal cancer (CRC). Resveratrol is able to utilize β1-integrin receptors, strongly expressed in CRC cells, to transmit and exert anti-carcinogenic signals, but wheth...

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Detalles Bibliográficos
Autores principales: Brockmueller, Aranka, Girisa, Sosmitha, Kunnumakkara, Ajaikumar B., Shakibaei, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003050/
https://www.ncbi.nlm.nih.gov/pubmed/36902421
http://dx.doi.org/10.3390/ijms24054988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003050/
https://www.ncbi.nlm.nih.gov/pubmed/36902421
http://dx.doi.org/10.3390/ijms24054988

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