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Resveratrol Modulates Chemosensitisation to 5-FU via β1-Integrin/HIF-1α Axis in CRC Tumor Microenvironment
Frequent development of resistance to chemotherapeutic agents such as 5-flourouracil (5-FU) complicates the treatment of advanced colorectal cancer (CRC). Resveratrol is able to utilize β1-integrin receptors, strongly expressed in CRC cells, to transmit and exert anti-carcinogenic signals, but wheth...
Autores principales: | Brockmueller, Aranka, Girisa, Sosmitha, Kunnumakkara, Ajaikumar B., Shakibaei, Mehdi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003050/ https://www.ncbi.nlm.nih.gov/pubmed/36902421 http://dx.doi.org/10.3390/ijms24054988 |
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