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Influence of Genetic Variations in miRNA and Genes Encoding Proteins in the miRNA Synthesis Complex on Toxicity of the Treatment of Pediatric B-Cell ALL in the Brazilian Amazon

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer in the world. Single nucleotide variants (SNVs) in miRNA and genes encoding proteins of the miRNA synthesis complex (SC) may affect the processing of drugs used in the treatment of ALL, resulting in treatment-related toxicities (...

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Detalles Bibliográficos
Autores principales: da Silva Menezes, Elisa, de Moraes, Francisco Cezar Aquino, de Nazaré Cohen-Paes, Amanda, Wanderley, Alayde Vieira, Pereira, Esdras Edgar Batista, Pastana, Lucas Favacho, Modesto, Antônio André Conde, de Assumpção, Paulo Pimentel, Burbano, Rommel Mario Rodríguez, dos Santos, Sidney Emanuel Batista, dos Santos, Ney Pereira Carneiro, Fernandes, Marianne Rodrigues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003057/
https://www.ncbi.nlm.nih.gov/pubmed/36901860
http://dx.doi.org/10.3390/ijms24054431