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Functional Characterization of Transgenic Mice Overexpressing Human 15-Lipoxygenase-1 (ALOX15) under the Control of the aP2 Promoter

Arachidonic acid lipoxygenases (ALOX) have been implicated in the pathogenesis of inflammatory, hyperproliferative, neurodegenerative, and metabolic diseases, but the physiological function of ALOX15 still remains a matter of discussion. To contribute to this discussion, we created transgenic mice (...

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Detalles Bibliográficos
Autores principales: Heydeck, Dagmar, Ufer, Christoph, Kakularam, Kumar R., Rothe, Michael, Liehr, Thomas, Poulain, Philippe, Kuhn, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003068/
https://www.ncbi.nlm.nih.gov/pubmed/36902243
http://dx.doi.org/10.3390/ijms24054815