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Molecular Dynamics Assessment of Mechanical Properties of the Thin Filaments in Cardiac Muscle

Contraction of cardiac muscle is regulated by Ca [Formula: see text] ions via regulatory proteins, troponin (Tn), and tropomyosin (Tpm) associated with the thin (actin) filaments in myocardial sarcomeres. The binding of Ca [Formula: see text] to a Tn subunit causes mechanical and structural changes...

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Detalles Bibliográficos
Autores principales: Koubassova, Natalia A., Tsaturyan, Andrey K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003134/
https://www.ncbi.nlm.nih.gov/pubmed/36902223
http://dx.doi.org/10.3390/ijms24054792