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Molecular Dynamics Assessment of Mechanical Properties of the Thin Filaments in Cardiac Muscle
Contraction of cardiac muscle is regulated by Ca [Formula: see text] ions via regulatory proteins, troponin (Tn), and tropomyosin (Tpm) associated with the thin (actin) filaments in myocardial sarcomeres. The binding of Ca [Formula: see text] to a Tn subunit causes mechanical and structural changes...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003134/ https://www.ncbi.nlm.nih.gov/pubmed/36902223 http://dx.doi.org/10.3390/ijms24054792 |