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S1P Released by SGPL1-Deficient Astrocytes Enhances Astrocytic ATP Production via S1PR(2,4), Thus Keeping Autophagy in Check: Potential Consequences for Brain Health

Astrocytes are critical players in brain health and disease. Sphingosine-1-phosphate (S1P), a bioactive signaling lipid, is involved in several vital processes, including cellular proliferation, survival, and migration. It was shown to be crucial for brain development. Its absence is embryonically l...

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Detalles Bibliográficos
Autores principales: Alam, Shah, Afsar, Sumaiya Yasmeen, Van Echten-Deckert, Gerhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003137/
https://www.ncbi.nlm.nih.gov/pubmed/36902011
http://dx.doi.org/10.3390/ijms24054581