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S1P Released by SGPL1-Deficient Astrocytes Enhances Astrocytic ATP Production via S1PR(2,4), Thus Keeping Autophagy in Check: Potential Consequences for Brain Health
Astrocytes are critical players in brain health and disease. Sphingosine-1-phosphate (S1P), a bioactive signaling lipid, is involved in several vital processes, including cellular proliferation, survival, and migration. It was shown to be crucial for brain development. Its absence is embryonically l...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003137/ https://www.ncbi.nlm.nih.gov/pubmed/36902011 http://dx.doi.org/10.3390/ijms24054581 |