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Understanding Passive Membrane Permeation of Peptides: Physical Models and Sampling Methods Compared

The early characterization of drug membrane permeability is an important step in pharmaceutical developments to limit possible late failures in preclinical studies. This is particularly crucial for therapeutic peptides whose size generally prevents them from passively entering cells. However, a sequ...

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Detalles Bibliográficos
Autores principales: Mazzanti, Liuba, Ha-Duong, Tâp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003141/
https://www.ncbi.nlm.nih.gov/pubmed/36902455
http://dx.doi.org/10.3390/ijms24055021