DNA Damage and Its Role in Cancer Therapeutics

DNA damage is a double-edged sword in cancer cells. On the one hand, DNA damage exacerbates gene mutation frequency and cancer risk. Mutations in key DNA repair genes, such as breast cancer 1 (BRCA1) and/or breast cancer 2 (BRCA2), induce genomic instability and promote tumorigenesis. On the other h...

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Detalles Bibliográficos
Autores principales: Moon, Jaeyoung, Kitty, Ichiwa, Renata, Kusuma, Qin, Sisi, Zhao, Fei, Kim, Wootae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003233/
https://www.ncbi.nlm.nih.gov/pubmed/36902170
http://dx.doi.org/10.3390/ijms24054741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003233/
https://www.ncbi.nlm.nih.gov/pubmed/36902170
http://dx.doi.org/10.3390/ijms24054741

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