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Hepatocellular Carcinoma Cell-Derived Exosomal miR-21-5p Induces Macrophage M2 Polarization by Targeting RhoB

M2-like polarized tumor-associated macrophages (TAMs) are the major component of infiltrating immune cells in hepatocellular carcinoma (HCC), which have been proved to exhibit significant immunosuppressive and pro-tumoral effects. However, the underlying mechanism of the tumor microenvironment (TME)...

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Detalles Bibliográficos
Autores principales: Yu, Haiyang, Pan, Jing, Zheng, Siyue, Cai, Deyang, Luo, Aixiang, Xia, Zanxian, Huang, Jufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003272/
https://www.ncbi.nlm.nih.gov/pubmed/36902024
http://dx.doi.org/10.3390/ijms24054593