Ergotamine Stimulates Human 5-HT(4)-Serotonin Receptors and Human H(2)-Histamine Receptors in the Heart

Ergotamine (2′-methyl-5′α-benzyl-12′-hydroxy-3′,6′,18-trioxoergotaman) is a tryptamine-related alkaloid from the fungus Claviceps purpurea. Ergotamine is used to treat migraine. Ergotamine can bind to and activate several types of 5-HT(1)-serotonin receptors. Based on the structural formula of ergot...

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Detalles Bibliográficos
Autores principales: Jacob, Hannes, Braekow, Pauline, Schwarz, Rebecca, Höhm, Christian, Kirchhefer, Uwe, Hofmann, Britt, Neumann, Joachim, Gergs, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003312/
https://www.ncbi.nlm.nih.gov/pubmed/36902177
http://dx.doi.org/10.3390/ijms24054749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003312/
https://www.ncbi.nlm.nih.gov/pubmed/36902177
http://dx.doi.org/10.3390/ijms24054749

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