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Degranulation of Murine Resident Cochlear Mast Cells: A Possible Factor Contributing to Cisplatin-Induced Ototoxicity and Neurotoxicity

Permanent hearing loss is one of cisplatin’s adverse effects, affecting 30–60% of cancer patients treated with that drug. Our research group recently identified resident mast cells in rodents’ cochleae and observed that the number of mast cells changed upon adding cisplatin to cochlear explants. Her...

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Detalles Bibliográficos
Autores principales: Karayay, Betül, Olze, Heidi, Szczepek, Agnieszka J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003316/
https://www.ncbi.nlm.nih.gov/pubmed/36902051
http://dx.doi.org/10.3390/ijms24054620