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Regulation of MAPK Signaling Pathways by the Large HERC Ubiquitin Ligases
Protein ubiquitylation acts as a complex cell signaling mechanism since the formation of different mono- and polyubiquitin chains determines the substrate’s fate in the cell. E3 ligases define the specificity of this reaction by catalyzing the attachment of ubiquitin to the substrate protein. Thus,...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003351/ https://www.ncbi.nlm.nih.gov/pubmed/36902336 http://dx.doi.org/10.3390/ijms24054906 |