SPRED2: A Novel Regulator of Epithelial-Mesenchymal Transition and Stemness in Hepatocellular Carcinoma Cells

The downregulation of SPRED2, a negative regulator of the ERK1/2 pathway, was previously detected in human cancers; however, the biological consequence remains unknown. Here, we investigated the effects of SPRED2 loss on hepatocellular carcinoma (HCC) cell function. Human HCC cell lines, expressing...

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Detalles Bibliográficos
Autores principales: Gao, Tong, Yang, Xu, Fujisawa, Masayoshi, Ohara, Toshiaki, Wang, Tianyi, Tomonobu, Nahoko, Sakaguchi, Masakiyo, Yoshimura, Teizo, Matsukawa, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003366/
https://www.ncbi.nlm.nih.gov/pubmed/36902429
http://dx.doi.org/10.3390/ijms24054996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003366/
https://www.ncbi.nlm.nih.gov/pubmed/36902429
http://dx.doi.org/10.3390/ijms24054996

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