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Endostatin 33 Peptide Is a Deintegrin α6β1 Agent That Exerts Antitumor Activity by Inhibiting the PI3K-Akt Signaling Pathway in Prostate Cancer

Background: Prostate cancer (PCa) is the leading cause of death in men and has poor therapeutic outcomes. Methods: A novel endostatin 33 peptide was synthesized by adding a specific QRD sequence on the basis of the endostatin 30 peptide (PEP06) with antitumor activity. Then, bioinformatic analysis a...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Wang, Chang-Lin, Pang, Zhong-Qi, Gao, Ke, Shen, Lin-Kun, Xu, Wan-Hai, Ren, Ming-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003382/
https://www.ncbi.nlm.nih.gov/pubmed/36902648
http://dx.doi.org/10.3390/jcm12051861