Overexpression of a Novel Noxo1 Mutant Increases Ros Production and Noxo1 Relocalisation

Noxo1, the organizing element of the Nox1-dependent NADPH oxidase complex responsible for producing reactive oxygen species, has been described to be degraded by the proteasome. We mutated a D-box in Noxo1 to express a protein with limited degradation and capable of maintaining Nox1 activation. Wild...

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Detalles Bibliográficos
Autores principales: Benssouina, Fatima-Zahra, Parat, Fabrice, Villard, Claude, Leloup, Ludovic, Garrouste, Françoise, Sabatier, Jean-marc, Ferhat, Lotfi, Kovacic, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003393/
https://www.ncbi.nlm.nih.gov/pubmed/36902094
http://dx.doi.org/10.3390/ijms24054663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003393/
https://www.ncbi.nlm.nih.gov/pubmed/36902094
http://dx.doi.org/10.3390/ijms24054663

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