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Overexpression of a Novel Noxo1 Mutant Increases Ros Production and Noxo1 Relocalisation
Noxo1, the organizing element of the Nox1-dependent NADPH oxidase complex responsible for producing reactive oxygen species, has been described to be degraded by the proteasome. We mutated a D-box in Noxo1 to express a protein with limited degradation and capable of maintaining Nox1 activation. Wild...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003393/ https://www.ncbi.nlm.nih.gov/pubmed/36902094 http://dx.doi.org/10.3390/ijms24054663 |