WNT3a Signaling Inhibits Aromatase Expression in Breast Adipose Fibroblasts—A Possible Mechanism Supporting the Loss of Estrogen Responsiveness of Triple-Negative Breast Cancers

Estrogen-dependent breast cancers rely on a constant supply of estrogens and expression of estrogen receptors. Local biosynthesis, by aromatase in breast adipose fibroblasts (BAFs), is their most important source for estrogens. Triple-negative breast cancers (TNBC) rely on other growth-promoting sig...

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Detalles Bibliográficos
Autores principales: Kaiser, Alexander, Eiselt, Gabriele, Bechler, Joachim, Huber, Otmar, Schmidt, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003471/
https://www.ncbi.nlm.nih.gov/pubmed/36902090
http://dx.doi.org/10.3390/ijms24054654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003471/
https://www.ncbi.nlm.nih.gov/pubmed/36902090
http://dx.doi.org/10.3390/ijms24054654

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