BRCA Mutations—The Achilles Heel of Breast, Ovarian and Other Epithelial Cancers

Two related tumor suppressor genes, BRCA1 and BRCA2, attract a lot of attention from both fundamental and clinical points of view. Oncogenic hereditary mutations in these genes are firmly linked to the early onset of breast and ovarian cancers. However, the molecular mechanisms that drive extensive...

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Detalles Bibliográficos
Autores principales: Loboda, Anna P., Adonin, Leonid S., Zvereva, Svetlana D., Guschin, Dmitri Y., Korneenko, Tatyana V., Telegina, Alexandra V., Kondratieva, Olga K., Frolova, Sofia E., Pestov, Nikolay B., Barlev, Nick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003548/
https://www.ncbi.nlm.nih.gov/pubmed/36902416
http://dx.doi.org/10.3390/ijms24054982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003548/
https://www.ncbi.nlm.nih.gov/pubmed/36902416
http://dx.doi.org/10.3390/ijms24054982

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