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Discovery and Optimization of Neutralizing SARS-CoV-2 Antibodies Using ALTHEA Gold Plus Libraries™

We recently reported the isolation and characterization of anti-SARS-CoV-2 antibodies from a phage display library built with the VH repertoire of a convalescent COVID-19 patient, paired with four naïve synthetic VL libraries. One of the antibodies, called IgG-A7, neutralized the Wuhan, Delta (B.1.6...

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Detalles Bibliográficos
Autores principales: Guzmán-Bringas, Omar U., Gómez-Castellano, Keyla M., González-González, Edith, Salinas-Trujano, Juana, Vázquez-Leyva, Said, Vallejo-Castillo, Luis, Pérez-Tapia, Sonia M., Almagro, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003557/
https://www.ncbi.nlm.nih.gov/pubmed/36902040
http://dx.doi.org/10.3390/ijms24054609