Tryptophan Hydroxylase-2-Mediated Serotonin Biosynthesis Suppresses Cell Reprogramming into Pluripotent State

The monoamine neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has important functions both in the neural system and during embryonic development in mammals. In this study, we set out to investigate whether and how endogenous serotonin affects reprogramming to pluripotency. As serotonin is syn...

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Detalles Bibliográficos
Autores principales: Sinenko, Sergey A., Kuzmin, Andrey A., Skvortsova, Elena V., Ponomartsev, Sergey V., Efimova, Evgeniya V., Bader, Michael, Alenina, Natalia, Tomilin, Alexey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003565/
https://www.ncbi.nlm.nih.gov/pubmed/36902295
http://dx.doi.org/10.3390/ijms24054862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003565/
https://www.ncbi.nlm.nih.gov/pubmed/36902295
http://dx.doi.org/10.3390/ijms24054862

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