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Tryptophan Hydroxylase-2-Mediated Serotonin Biosynthesis Suppresses Cell Reprogramming into Pluripotent State
The monoamine neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has important functions both in the neural system and during embryonic development in mammals. In this study, we set out to investigate whether and how endogenous serotonin affects reprogramming to pluripotency. As serotonin is syn...
Autores principales: | Sinenko, Sergey A., Kuzmin, Andrey A., Skvortsova, Elena V., Ponomartsev, Sergey V., Efimova, Evgeniya V., Bader, Michael, Alenina, Natalia, Tomilin, Alexey N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003565/ https://www.ncbi.nlm.nih.gov/pubmed/36902295 http://dx.doi.org/10.3390/ijms24054862 |
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